Responsibilities

We are looking for a highly motivated candidate for the role of Purification Scientist (Maternity Cover) to join our purification team within the customer’s analytical group.

A successful candidate will be responsible for delivering and isolating high purity samples as part of the Centralised Achiral Purification Service (CAPS).

In this position, the candidate could develop a career as part of the PerkinElmer OneSource Scientific Services to support a major pharmaceutical company at the Stevenage Science Campus.

Job Responsibilities

Operational

• Deliver a flow process, involving varied instrumentation platforms, to enable the isolation of compounds of interest from crude mixtures.

• Utilise relevant analytical instrumentation for separations method development; primarily analytical UPLC-MS.

• Operate mass-directed automated purification (MDAP) HPLC platforms to purify complex, crude sample mixtures.

• Identify desired chromatographic fractions and consolidate for isolation using liquid handling robots.

• Removal of chromatographic purification solvents by lyophilisation and generation of post-purification analysis samples for multiple techniques, such as UPLC-MS and NMR.

• Use liquid handling technology and other appropriate instrumentation (including nitrogen dry-down units and lyophilisation units) to dispense purified compounds for ongoing screening.

• Oversee the collection of appropriate analytical data to characterise and register final drug candidate molecules prior to organising submission for screening.

• Document purification conditions and method development used to isolate compounds and provide this information to the originating chemist.

• Maintain instrumentation as appropriate and escalate any identified instrumentation or hardware issues.

• Support CAPS scientists with evaluations of new chromatographic systems and related processes as appropriate.

• Operate and maintain laboratory equipment in accordance with appropriate internal maintenance SOPs and work instructions.

• Collect service metrics where applicable.

• Follow all safety protocols and operating requirements as defined by local management and customer policy.

Qualifications/Personal Qualities

We are looking for professionals with these required skills to achieve our goals:

• Bachelor’s degree or 2 years of experience in chemistry, analytical chemistry or a similar scientific discipline, though open to A-Level school leavers with strong interest in science

• Working familiarity with different analytical and preparative techniques are desired.

• Strong desire to learn, Self-motivated, pro-active and solution driven.

• Outstanding verbal and written communication.

• Basic preparative instrumentation knowledge including simple maintenance and repair would be welcome.

• Ability to multitask across purification and analysis.

• Ability to manage the workflow within the group.

• Ability to analyse chromatographic data and make decisions for follow up experiments

• Excellent Customer Service and Customer Relation skills

Physical/Mental Demands

The overall physical exertion of this position may require the candidate to:

• Sit or stand 4-5 hours in laboratory areas.

• Reach above/below the shoulder, bend at the knees and waist.

• Office work activities, including computer-based activities.

• Work around moving laboratory equipment and machinery.

• Use of personal protective equipment in laboratory.

• Work with hazardous compounds and chemicals in compliance with local safety rules and regulations.

Working Environment

• Must be able to work in a laboratory, controlled environment requiring personal protective equipment.

• Job pace may be fast and job completion demands may be high.

• Employee will be required to manage hazardous wastes in compliance with local company procedures & UK hazardous waste regulations. Duties may include: identifying, handling, generating, accumulating, storing, labelling and appropriate disposal.

Your Growth, Your Development, Our Help

As a company, PerkinElmer has been recognised for its Inclusion and Development of its employees (2022 Most Loved Workplaces #8), we develop your career journey by utilising your skills and interests to get a fully introduction into the science industry for you to develop as you want.

We are learning from other recognised companies to then develop programs to make the employee experience amongst the best, as we see the importance to the product we deliver, is a result of the investment and respect in our staff.